Description
Corning Polypropylene Cryogenic Vial – 2 mL, External Thread, Round Bottom, Non-Skirted, Sterile (MPN: 430661)
The Corning 430661 is a premium, bioprocess-grade 2 mL cryogenic storage vial engineered for the ultra-low temperature preservation and archiving of sensitive biological samples, cell cultures, and genomic materials. Precision-molded from heavy-duty, virgin polypropylene, this tube features a non-skirted round bottom geometry optimized for maximum fluid recovery and uniform freezing paths. The vial utilizes an external-thread cap design paired with an integrated silicone washer, establishing a hermetic mechanical seal that resists fluid leaking and sample loss. Validated sterile and certified free of detectable nucleases, these high-performance storage vials reliably safeguard target biomolecules within deep-freeze environments down to vapor-phase liquid nitrogen conditions.
Technical Performance and Design
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External Thread Contamination Defense: Designed with an externally threaded cap assembly that covers the outer rim of the vial. This architecture minimizes the risk of sample contamination or touch-contact carryover during manual or automated opening loops, unlike internal-thread designs.
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Silicone Washer Hermetic Seal: Outfitted with a premium, heavy-duty silicone washer nested inside the polypropylene cap. Under standard torque, the gasket forms a positive physical barrier that retains internal pressures and blocks environmental gaseous exchange during storage loops.
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Ultra-Low Deep Freeze Integrity: Manufactured from specialized high-molecular-weight polypropylene rated to withstand extreme cryopreservation environments down to minus 196 C, preventing material embrittlement, stress cracking, or structural failures in cold vaults.
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High-Contrast Graduation Spotting: Features crisp, permanent black volumetric graduation markers running up the clear side wall, paired with an oversized matte white writing patch to facilitate clear, smudge-resistant sample indexing.
Product Specifications
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Catalog Number / MPN: 430661
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Manufacturer / Brand: Corning Life Sciences
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Volumetric Storage Capacity: 2.0 mL (2 milliliters)
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Thread Configuration: External Threaded Cap Assembly
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Vial Base Geometry: Round Bottom, Non-Skirted (Not Self-Standing)
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Material Composition: Ultra-Pure Virgin Polypropylene (PP)
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Thermal Endurance Horizon: Rated for safe continuous use from minus 196 C up to plus 121 C
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Sterility / Purity Profile: Gamma Irradiated Sterile, Non-Pyrogenic, and certified free of detectable RNase and DNase
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Standard Packaging: Case of 500 Vials total (Arranged as 10 inner resealable safety bags containing 50 vials per pack)
Key Benefits and Applications
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Vapor-Phase Cryopreservation: The industry-standard storage vessel for banking valuable mammalian cell lines, primary tissues, and cell pellets inside the vapor phase of liquid nitrogen tanks.
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Genomics and Biobanking Repositories: Extensively deployed across clinical tissue banks and research centers for archiving nucleic acid extractions, plasmid stocks, serum aliquots, and protein standards.
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Color-Coded Cap Inserts: The flat cap surface accepts snap-in polypropylene color-coding inserts, allowing technicians to systematically map and visually categorize large sample libraries across storage grids.
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Safety Storage Protocol Notice: For operational safety, cryogenic vials must always be stored exclusively inside the vapor phase above liquefied nitrogen gas; do not submerge vials directly into liquid-phase nitrogen to prevent fluid entry and expansion hazards upon warming.
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